Cargando…

Correlation of Gli1 and HER2 expression in gastric cancer: Identification of novel target

HER2 becomes the standard of care for guiding adjuvant treatment of gastric cancer with trastuzumab in recent years. However, the usage of this target agent is still limited because of the resistance to trastuzumab or the negative expression of HER2 in tumor tissues. The Gli1 and HER2 both play an i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shao, Xinyu, Kuai, Xiaoyi, Pang, Zhi, Zhang, Liping, Wu, Longyun, Xu, Lijuan, Zhou, Chunli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762756/ https://www.ncbi.nlm.nih.gov/pubmed/29321573 http://dx.doi.org/10.1038/s41598-017-17435-6

Ejemplares similares

Rab1A promotes proliferation and migration abilities via regulation of the HER2/AKT-independent mTOR/S6K1 pathway in colorectal cancer
por: Cheng, Zhengwu, et al.
Publicado: (2019)

Expression analysis and implication of Rab1A in gastrointestinal relevant tumor
por: Xu, Menglin, et al.
Publicado: (2019)

Identification of RegIV as a Novel GLI1 Target Gene in Human Pancreatic Cancer
por: Wang, Feng, et al.
Publicado: (2011)

Correction: Identification of RegIV as a Novel GLI1 Target Gene in Human Pancreatic Cancer
por: Wang, Feng, et al.
Publicado: (2011)

Leaky Gut in IBD: Intestinal Barrier–Gut Microbiota Interaction
por: Yu, Shunying, et al.
Publicado: (2022)

Propensity score matching analysis to evaluate efficacy of polyethylene oxide adhesive on preventing delayed bleeding after gastric endoscopic submucosal dissection
por: Yu, Yang, et al.
Publicado: (2022)

Identification of novel GLI1 target genes and regulatory circuits in human cancer cells
por: Diao, Yumei, et al.
Publicado: (2018)

Identification of a novel tumor angiogenesis inhibitor targeting Shh/Gli1 signaling pathway in Non-small cell lung cancer
por: Lei, Xueping, et al.
Publicado: (2020)

Flotillin2 Expression Correlates with HER2 Levels and Poor Prognosis in Gastric Cancer
por: Zhu, Zhi, et al.
Publicado: (2013)

A Novel Therapeutic siRNA Nanoparticle Designed for Dual-Targeting CD44 and Gli1 of Gastric Cancer Stem Cells
por: Yao, Hongjuan, et al.
Publicado: (2020)

Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish
por: Wang, Xingang, et al.
Publicado: (2013)

Clinical implications of plasma ctDNA features and dynamics in gastric cancer treated with HER2‐targeted therapies
por: Zhang, Cheng, et al.
Publicado: (2020)

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1
por: Schneider, Philipp, et al.
Publicado: (2015)

Gli as a Novel Therapeutic Target in Malignant Pleural Mesothelioma
por: Li, Hui, et al.
Publicado: (2013)

Prognostic significance of different molecular typing methods and immune status based on RNA sequencing in HR-positive and HER2-negative early-stage breast cancer
por: Ren, Xinyu, et al.
Publicado: (2022)

HER2 Inhibition in Gastric Cancer—Novel Therapeutic Approaches for an Established Target
por: Fong, Caroline, et al.
Publicado: (2022)

Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes
por: Ali, Shabana Amanda, et al.
Publicado: (2019)

Gli1 regulates stemness characteristics in gastric adenocarcinoma
por: Qi, Wenbo, et al.
Publicado: (2020)

The tripeptide N-Cbz-βGly-Gly-Gly-Obz
por: Nicholas, Sumesh
Publicado: (2015)

Generation of a Novel SORT1×HER2 Bispecific Antibody–Drug Conjugate Targeting HER2-Low-Expression Tumor
por: Zhuang, Weiliang, et al.
Publicado: (2023)

Targeting HER2-positive gastric cancer with a novel (18)F-labeled Z(HER2:342) probe
por: Pan, Yunyun, et al.
Publicado: (2019)

Beyond Chemotherapy, PD-1, and HER-2: Novel Targets for Gastric and Esophageal Cancer
por: Siddiqui, Ali Zubair, et al.
Publicado: (2021)

Targeting GLI Transcription Factors in Cancer
por: Didiasova, Miroslava, et al.
Publicado: (2018)

Correction: Corrigendum: Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1
por: Schneider, Philipp, et al.
Publicado: (2015)

Expression of Legumain Correlates with Prognosis and Metastasis in Gastric Carcinoma
por: Guo, Pengtao, et al.
Publicado: (2013)

Specific HER2 Exon 20 Gly776 Deletion-Insertions in Non-Small Cell Lung Cancer: Structural Analysis and Sensitivity to HER2-Targeted Tyrosine Kinase Inhibitors
por: Yang, Guangjian, et al.
Publicado: (2022)

Immunoproteomics based identification of thioredoxin reductase GliT and novel Aspergillus fumigatus antigens for serologic diagnosis of invasive aspergillosis
por: Shi, Li-ning, et al.
Publicado: (2012)

Serum HER 2 Extracellular Domain Level Is Correlated with Tissue HER 2 Status in Metastatic Gastric or Gastro-Oesophageal Junction Adenocarcinoma
por: Dai, Shu-Qin, et al.
Publicado: (2013)

Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative and HER2-enriched breast cancers
por: Sirkisoon, Sherona R., et al.
Publicado: (2018)

Ascl1/Mash1 Is a Novel Target of Gli2 during Gli2-Induced Neurogenesis in P19 EC Cells
por: Voronova, Anastassia, et al.
Publicado: (2011)

Novel HER2-Directed Treatments in Advanced Gastric Carcinoma: AnotHER Paradigm Shift?
por: Ricci, Angela Dalia, et al.
Publicado: (2021)

Complex formation constant of ferric ion with Gly, Pro-Hyp and Gly-Pro-Hyp
por: Zhi, Mingyu, et al.
Publicado: (2018)

Prognostic and clinicopathological value of Gli-1 expression in gastric cancer: A meta-analysis
por: Lu, Li, et al.
Publicado: (2016)

GLI1: A Therapeutic Target for Cancer
por: Avery, Justin T., et al.
Publicado: (2021)

Identification of the gene transcription repressor domain of Gli3
por: Tsanev, Robert, et al.
Publicado: (2009)

HER2 protein expression correlates with Lauren classification and P53 in gastric cancer patients
por: Chu, Yiming, et al.
Publicado: (2022)

Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development
por: Milla, Luis A, et al.
Publicado: (2012)

Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells
por: Vlčková, K, et al.
Publicado: (2016)

A Novel C(2)H(2) Transcription Factor that Regulates gliA Expression Interdependently with GliZ in Aspergillus fumigatus
por: Schoberle, Taylor J., et al.
Publicado: (2014)

HER2 screening data from ToGA: targeting HER2 in gastric and gastroesophageal junction cancer
por: Van Cutsem, Eric, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qo7oo6fe9a2lr9g4eaiocvn1fd