Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunction in Alzheimer’s disease model

Alzheimer’s disease (AD) is an incurable neurodegenerative disease characterised clinically by learning and memory impairments. Amyloid beta (Aβ) peptide-induced synaptic dysfunction is a pathological process associated with early-stage AD. Here, we show that paracrine action of human umbilical cord...

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Detalles Bibliográficos
Autores principales: Kim, Dong Hyun, Lim, Hoon, Lee, Dahm, Choi, Soo Jin, Oh, Wonil, Yang, Yoon Sun, Oh, Jeong Su, Hwang, Hyun Ho, Jeon, Hong Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762817/
https://www.ncbi.nlm.nih.gov/pubmed/29321508
http://dx.doi.org/10.1038/s41598-017-18542-0

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