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Loss of tolerance to gut immunity protein, glycoprotein 2 (GP2) is associated with progressive disease course in primary sclerosing cholangitis

Glycoprotein 2[GP2] is a specific target of pancreatic autoantibodies[PAbs] in Crohn’s disease(CD) and is involved in gut innate immunity processes. Our aim was to evaluate the prevalence and prognostic potential of PAbs in primary sclerosing cholangitis(PSC). Sixty-five PSC patients were tested for...

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Detalles Bibliográficos
Autores principales: Tornai, Tamas, Tornai, David, Sipeki, Nora, Tornai, Istvan, Alsulaimani, Rayan, Fechner, Kai, Roggenbuck, Dirk, Norman, Gary L., Veres, Gabor, Par, Gabriella, Par, Alajos, Szalay, Ferenc, Lakatos, Peter Laszlo, Antal-Szalmas, Peter, Papp, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762861/
https://www.ncbi.nlm.nih.gov/pubmed/29321484
http://dx.doi.org/10.1038/s41598-017-18622-1