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Tousled-like kinase 1 is a negative regulator of core transcription factors in murine embryonic stem cells

Although the differentiation of pluripotent cells in embryonic stem cells (ESCs) is often associated with protein kinase-mediated signaling pathways and Tousled-like kinase 1 (Tlk1) is required for development in several species, the role of Tlk1 in ESC function remains unclear. Here, we used mouse...

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Detalles Bibliográficos
Autores principales: Lee, Jina, Kim, Min Seong, Park, Su Hyung, Jang, Yeun Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762884/
https://www.ncbi.nlm.nih.gov/pubmed/29321513
http://dx.doi.org/10.1038/s41598-017-18628-9