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Tousled-like kinase 1 is a negative regulator of core transcription factors in murine embryonic stem cells
Although the differentiation of pluripotent cells in embryonic stem cells (ESCs) is often associated with protein kinase-mediated signaling pathways and Tousled-like kinase 1 (Tlk1) is required for development in several species, the role of Tlk1 in ESC function remains unclear. Here, we used mouse...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762884/ https://www.ncbi.nlm.nih.gov/pubmed/29321513 http://dx.doi.org/10.1038/s41598-017-18628-9 |