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In vitro transfection of anti-tumor miR-101 induces BIM, a pro-apoptotic protein, expression in acute myeloid leukemia (AML)

Acute myeloid leukemia (AML) frequently relapses after initial treatment, though it is possible that drug resistance occurs. Hence, it seems necessary to develop novel therapies such as gene therapy specifically via miRNA transfection. MicroRNA-101 has been considered as a tumor suppressor in differ...

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Detalles Bibliográficos
Autores principales: Nikoonahad Lotfabadi, Narges, Mohseni Kouchesfahani, Homa, Sheikhha, Mohammad Hasan, Kalantar, Seyed Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763080/
https://www.ncbi.nlm.nih.gov/pubmed/29333128
http://dx.doi.org/10.17179/excli2017-721

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