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Follicular thyroid cancer avid on C-11 Methionine PET/CT
A case of follicular thyroid cancer with intense focal Methionine uptake on 11C-Methionine PET/CT is reported here. The use of 11C-Methionine PET in differentiated thyroid cancer is currently being investigated as a surrogate tracer compared to the more widely used 18F-FDG PET. This case illustrates...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763279/ https://www.ncbi.nlm.nih.gov/pubmed/29340158 http://dx.doi.org/10.1530/EDM-17-0151 |
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author | Jochumsen, Mads Ryø Iversen, Peter Arveschoug, Anne Kirstine |
author_facet | Jochumsen, Mads Ryø Iversen, Peter Arveschoug, Anne Kirstine |
author_sort | Jochumsen, Mads Ryø |
collection | PubMed |
description | A case of follicular thyroid cancer with intense focal Methionine uptake on 11C-Methionine PET/CT is reported here. The use of 11C-Methionine PET in differentiated thyroid cancer is currently being investigated as a surrogate tracer compared to the more widely used 18F-FDG PET. This case illustrates the potential incremental value of this modality, not only in the localizing of parathyroid adenoma, but also indicating that 11C-Methionine PET might have a potential of increasing the pretest likelihood of thyroid malignancy in a cold nodule with highly increased Sestamibi uptake. LEARNING POINTS: 11C-Methionine PET/CT and 18F-Fluorocholine PET/CT often visualizes the parathyroid adenoma in case of negative Tc-99m-MIBI SPECT/CT. A cold nodule in Tc-99m Pertechnetat thyroid scintigraphy with a negative Sestamibi scintigraphy has a very low probability of being malignant. However, the pretest likelihood of thyroid cancer in a cold nodule with increased Sestamibi uptake is low. 11C-Methionine PET might have a potential incremental value in increasing the pretest likelihood of thyroid malignancy in a cold nodule with highly increased Sestamibi uptake. |
format | Online Article Text |
id | pubmed-5763279 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Bioscientifica Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-57632792018-01-16 Follicular thyroid cancer avid on C-11 Methionine PET/CT Jochumsen, Mads Ryø Iversen, Peter Arveschoug, Anne Kirstine Endocrinol Diabetes Metab Case Rep Novel Diagnostic Procedure A case of follicular thyroid cancer with intense focal Methionine uptake on 11C-Methionine PET/CT is reported here. The use of 11C-Methionine PET in differentiated thyroid cancer is currently being investigated as a surrogate tracer compared to the more widely used 18F-FDG PET. This case illustrates the potential incremental value of this modality, not only in the localizing of parathyroid adenoma, but also indicating that 11C-Methionine PET might have a potential of increasing the pretest likelihood of thyroid malignancy in a cold nodule with highly increased Sestamibi uptake. LEARNING POINTS: 11C-Methionine PET/CT and 18F-Fluorocholine PET/CT often visualizes the parathyroid adenoma in case of negative Tc-99m-MIBI SPECT/CT. A cold nodule in Tc-99m Pertechnetat thyroid scintigraphy with a negative Sestamibi scintigraphy has a very low probability of being malignant. However, the pretest likelihood of thyroid cancer in a cold nodule with increased Sestamibi uptake is low. 11C-Methionine PET might have a potential incremental value in increasing the pretest likelihood of thyroid malignancy in a cold nodule with highly increased Sestamibi uptake. Bioscientifica Ltd 2018-01-05 /pmc/articles/PMC5763279/ /pubmed/29340158 http://dx.doi.org/10.1530/EDM-17-0151 Text en © 2018 The authors http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en_GB This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en_GB) . |
spellingShingle | Novel Diagnostic Procedure Jochumsen, Mads Ryø Iversen, Peter Arveschoug, Anne Kirstine Follicular thyroid cancer avid on C-11 Methionine PET/CT |
title | Follicular thyroid cancer avid on C-11 Methionine PET/CT |
title_full | Follicular thyroid cancer avid on C-11 Methionine PET/CT |
title_fullStr | Follicular thyroid cancer avid on C-11 Methionine PET/CT |
title_full_unstemmed | Follicular thyroid cancer avid on C-11 Methionine PET/CT |
title_short | Follicular thyroid cancer avid on C-11 Methionine PET/CT |
title_sort | follicular thyroid cancer avid on c-11 methionine pet/ct |
topic | Novel Diagnostic Procedure |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763279/ https://www.ncbi.nlm.nih.gov/pubmed/29340158 http://dx.doi.org/10.1530/EDM-17-0151 |
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