A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

This large multi‐center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi‐modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients with psychosis, 822 unaffected first‐degree relatives of patients, and 2,333 c...

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Detalles Bibliográficos
Autores principales: Ranlund, Siri, Calafato, Stella, Thygesen, Johan H., Lin, Kuang, Cahn, Wiepke, Crespo‐Facorro, Benedicto, de Zwarte, Sonja M.C., Díez, Álvaro, Di Forti, Marta, Iyegbe, Conrad, Jablensky, Assen, Jones, Rebecca, Hall, Mei‐Hua, Kahn, Rene, Kalaydjieva, Luba, Kravariti, Eugenia, McDonald, Colm, McIntosh, Andrew M., McQuillin, Andrew, Picchioni, Marco, Prata, Diana P., Rujescu, Dan, Schulze, Katja, Shaikh, Madiha, Toulopoulou, Timothea, van Haren, Neeltje, van Os, Jim, Vassos, Evangelos, Walshe, Muriel, Lewis, Cathryn, Murray, Robin M., Powell, John, Bramon, Elvira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763362/
https://www.ncbi.nlm.nih.gov/pubmed/28851104
http://dx.doi.org/10.1002/ajmg.b.32581

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