Cargando…

Dynamically analyzing cell interactions in biological environments using multiagent social learning framework

BACKGROUND: Biological environment is uncertain and its dynamic is similar to the multiagent environment, thus the research results of the multiagent system area can provide valuable insights to the understanding of biology and are of great significance for the study of biology. Learning in a multia...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Chengwei, Li, Xiaohong, Li, Shuxin, Feng, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763467/
https://www.ncbi.nlm.nih.gov/pubmed/29297360
http://dx.doi.org/10.1186/s13326-017-0142-0
_version_ 1783291894988537856
author Zhang, Chengwei
Li, Xiaohong
Li, Shuxin
Feng, Zhiyong
author_facet Zhang, Chengwei
Li, Xiaohong
Li, Shuxin
Feng, Zhiyong
author_sort Zhang, Chengwei
collection PubMed
description BACKGROUND: Biological environment is uncertain and its dynamic is similar to the multiagent environment, thus the research results of the multiagent system area can provide valuable insights to the understanding of biology and are of great significance for the study of biology. Learning in a multiagent environment is highly dynamic since the environment is not stationary anymore and each agent’s behavior changes adaptively in response to other coexisting learners, and vice versa. The dynamics becomes more unpredictable when we move from fixed-agent interaction environments to multiagent social learning framework. Analytical understanding of the underlying dynamics is important and challenging. RESULTS: In this work, we present a social learning framework with homogeneous learners (e.g., Policy Hill Climbing (PHC) learners), and model the behavior of players in the social learning framework as a hybrid dynamical system. By analyzing the dynamical system, we obtain some conditions about convergence or non-convergence. We experimentally verify the predictive power of our model using a number of representative games. Experimental results confirm the theoretical analysis. CONCLUSION: Under multiagent social learning framework, we modeled the behavior of agent in biologic environment, and theoretically analyzed the dynamics of the model. We present some sufficient conditions about convergence or non-convergence and prove them theoretically. It can be used to predict the convergence of the system.
format Online
Article
Text
id pubmed-5763467
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-57634672018-01-17 Dynamically analyzing cell interactions in biological environments using multiagent social learning framework Zhang, Chengwei Li, Xiaohong Li, Shuxin Feng, Zhiyong J Biomed Semantics Research BACKGROUND: Biological environment is uncertain and its dynamic is similar to the multiagent environment, thus the research results of the multiagent system area can provide valuable insights to the understanding of biology and are of great significance for the study of biology. Learning in a multiagent environment is highly dynamic since the environment is not stationary anymore and each agent’s behavior changes adaptively in response to other coexisting learners, and vice versa. The dynamics becomes more unpredictable when we move from fixed-agent interaction environments to multiagent social learning framework. Analytical understanding of the underlying dynamics is important and challenging. RESULTS: In this work, we present a social learning framework with homogeneous learners (e.g., Policy Hill Climbing (PHC) learners), and model the behavior of players in the social learning framework as a hybrid dynamical system. By analyzing the dynamical system, we obtain some conditions about convergence or non-convergence. We experimentally verify the predictive power of our model using a number of representative games. Experimental results confirm the theoretical analysis. CONCLUSION: Under multiagent social learning framework, we modeled the behavior of agent in biologic environment, and theoretically analyzed the dynamics of the model. We present some sufficient conditions about convergence or non-convergence and prove them theoretically. It can be used to predict the convergence of the system. BioMed Central 2017-09-20 /pmc/articles/PMC5763467/ /pubmed/29297360 http://dx.doi.org/10.1186/s13326-017-0142-0 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Zhang, Chengwei
Li, Xiaohong
Li, Shuxin
Feng, Zhiyong
Dynamically analyzing cell interactions in biological environments using multiagent social learning framework
title Dynamically analyzing cell interactions in biological environments using multiagent social learning framework
title_full Dynamically analyzing cell interactions in biological environments using multiagent social learning framework
title_fullStr Dynamically analyzing cell interactions in biological environments using multiagent social learning framework
title_full_unstemmed Dynamically analyzing cell interactions in biological environments using multiagent social learning framework
title_short Dynamically analyzing cell interactions in biological environments using multiagent social learning framework
title_sort dynamically analyzing cell interactions in biological environments using multiagent social learning framework
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763467/
https://www.ncbi.nlm.nih.gov/pubmed/29297360
http://dx.doi.org/10.1186/s13326-017-0142-0
work_keys_str_mv AT zhangchengwei dynamicallyanalyzingcellinteractionsinbiologicalenvironmentsusingmultiagentsociallearningframework
AT lixiaohong dynamicallyanalyzingcellinteractionsinbiologicalenvironmentsusingmultiagentsociallearningframework
AT lishuxin dynamicallyanalyzingcellinteractionsinbiologicalenvironmentsusingmultiagentsociallearningframework
AT fengzhiyong dynamicallyanalyzingcellinteractionsinbiologicalenvironmentsusingmultiagentsociallearningframework