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A linear programming computational framework integrates phosphor-proteomics and prior knowledge to predict drug efficacy

BACKGROUND: In recent years, the integration of ‘omics’ technologies, high performance computation, and mathematical modeling of biological processes marks that the systems biology has started to fundamentally impact the way of approaching drug discovery. The LINCS public data warehouse provides det...

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Detalles Bibliográficos
Autores principales:	Ji, Zhiwei, Wang, Bing, Yan, Ke, Dong, Ligang, Meng, Guanmin, Shi, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763468/ https://www.ncbi.nlm.nih.gov/pubmed/29322918 http://dx.doi.org/10.1186/s12918-017-0501-6

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