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Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis

BACKGROUND: Doxorubicin (DOX) is commonly used in the treatment of many types of cancers but its cardiotoxicity is limiting its clinical use. Beyond its anticoagulant action, enoxaparin (ENX), a low molecular weight heparin, has been shown to exert multiple pharmacological actions including antioxid...

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Detalles Bibliográficos
Autores principales: Shaker, Reem Ali, Abboud, Samer Hassan, Assad, Hayder Chasib, Hadi, Najah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763526/
https://www.ncbi.nlm.nih.gov/pubmed/29321061
http://dx.doi.org/10.1186/s40360-017-0184-z

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