Cargando…

Meta-analysis of human gene expression in response to Mycobacterium tuberculosis infection reveals potential therapeutic targets

BACKGROUND: With the global emergence of multi-drug resistant strains of Mycobacterium tuberculosis, new strategies to treat tuberculosis are urgently needed such as therapeutics targeting potential human host factors. RESULTS: Here we performed a statistical meta-analysis of human gene expression i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhang, Arat, Seda, Magid-Slav, Michal, Brown, James R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763539/ https://www.ncbi.nlm.nih.gov/pubmed/29321020 http://dx.doi.org/10.1186/s12918-017-0524-z

Ejemplares similares

Host Response to Respiratory Bacterial Pathogens as Identified by Integrated Analysis of Human Gene Expression Data
por: Smith, Steven B., et al.
Publicado: (2013)

Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis
por: Smith, Steven B., et al.
Publicado: (2012)

Mycobacterium tuberculosis: Pathogenesis and therapeutic targets
por: Yang, Jiaxing, et al.
Publicado: (2023)

From infection niche to therapeutic target: the intracellular lifestyle of Mycobacterium tuberculosis
por: Rankine-Wilson, Leah Isobella, et al.
Publicado: (2021)

Identification of gene targets against dormant phase Mycobacterium tuberculosis infections
por: Murphy, Dennis J, et al.
Publicado: (2007)

Mycobacterium marinum: a potential immunotherapy for Mycobacterium tuberculosis infection
por: Tian, Wei-wei, et al.
Publicado: (2013)

Potential Effect of Statins on Mycobacterium tuberculosis Infection
por: Guerra-De-Blas, Paola Del Carmen, et al.
Publicado: (2018)

Advancing Adjuvants for Mycobacterium tuberculosis Therapeutics
por: Enriquez, Ana B., et al.
Publicado: (2021)

Therapeutic Targeting of Protein Tyrosine Phosphatases from Mycobacterium tuberculosis
por: Ruddraraju, Kasi Viswanatharaju, et al.
Publicado: (2020)

Annotation depth confounds direct comparison of gene expression across species
por: Oziolor, Elias, et al.
Publicado: (2021)

Is Receptor-Interacting Protein Kinase 3 a Viable Therapeutic Target for Mycobacterium tuberculosis Infection?
por: Stutz, Michael D., et al.
Publicado: (2018)

Host Targeted Activity of Pyrazinamide in Mycobacterium tuberculosis Infection
por: Manca, Claudia, et al.
Publicado: (2013)

Bacteriophages of Mycobacterium tuberculosis, their diversity, and potential therapeutic uses: a review
por: Zeynali kelishomi, Fatemeh, et al.
Publicado: (2022)

Screening of natural compounds that targets glutamate racemase of Mycobacterium tuberculosis reveals the anti-tubercular potential of flavonoids
por: Pawar, Alka, et al.
Publicado: (2020)

Investigating the Role of Everolimus in mTOR Inhibition and Autophagy Promotion as a Potential Host-Directed Therapeutic Target in Mycobacterium tuberculosis Infection
por: Cerni, Stephen, et al.
Publicado: (2019)

Mycobacterium tuberculosis Infection and Tissue Factor Expression in Macrophages
por: Kothari, Hema, et al.
Publicado: (2012)

Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis
por: Martin, Constance J., et al.
Publicado: (2017)

Mycobacterium tuberculosis Secreted Proteins As Potential Biomarkers for the Diagnosis of Active Tuberculosis and Latent Tuberculosis Infection
por: Zhang, Caiqin, et al.
Publicado: (2014)

IRF1 as a potential biomarker in Mycobacterium tuberculosis infection
por: Wu, Liwei, et al.
Publicado: (2021)

Cofilin-1 as a potential biomarker for Mycobacterium tuberculosis infection
por: Xie, Yiping, et al.
Publicado: (2022)

Cargoes of exosomes function as potential biomarkers for Mycobacterium tuberculosis infection
por: Wang, Nan, et al.
Publicado: (2023)

Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis
por: Mowbray, Sherry L., et al.
Publicado: (2014)

Analysis of Differentially Expressed Proteins in Mycobacterium avium-Infected Macrophages Comparing with Mycobacterium tuberculosis-Infected Macrophages
por: Yang, Dongjun, et al.
Publicado: (2017)

The Biology of Mycobacterium Tuberculosis Infection
por: Delogu, Giovanni, et al.
Publicado: (2013)

Transcriptional Regulator Induced Phenotype screen reveals drug potentiators in Mycobacterium tuberculosis
por: Ma, Shuyi, et al.
Publicado: (2020)

Genotyping of ancient Mycobacterium tuberculosis strains reveals historic genetic diversity
por: Müller, Romy, et al.
Publicado: (2014)

T-Cell Exhaustion in Mycobacterium tuberculosis and Nontuberculous Mycobacteria Infection: Pathophysiology and Therapeutic Perspectives
por: Lombardi, Andrea, et al.
Publicado: (2021)

Genome analyses of 174 strains of Mycobacterium tuberculosis provide insight into the evolution of drug resistance and reveal potential drug targets
por: Verma, Helianthous, et al.
Publicado: (2021)

Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets
por: Ferraris, Davide M., et al.
Publicado: (2018)

Cytokine Biosignature of Active and Latent Mycobacterium Tuberculosis Infection in Children
por: Druszczynska, Magdalena, et al.
Publicado: (2021)

Identification of Missing Carbon Fixation Enzymes as Potential Drug Targets in Mycobacterium Tuberculosis
por: Katiyar, Amit, et al.
Publicado: (2018)

Autophagy Induction as a Host-Directed Therapeutic Strategy against Mycobacterium tuberculosis Infection
por: Adikesavalu, Harresh, et al.
Publicado: (2021)

Autophagy in Mycobacterium tuberculosis and HIV infections
por: Espert, Lucile, et al.
Publicado: (2015)

Regulatory T Cells in Mycobacterium tuberculosis Infection
por: Cardona, Paula, et al.
Publicado: (2019)

Is Mycobacterium tuberculosis infection life long?
por: Behr, Marcel A, et al.
Publicado: (2019)

Role of Interferons in Mycobacterium tuberculosis Infection
por: Shanmuganathan, Gaithrri, et al.
Publicado: (2022)

Mycobacterium tuberculosis Infection: Control and Treatment
por: Salina, Elena G.
Publicado: (2023)

The future of CRISPR in Mycobacterium tuberculosis infection
por: Zein-Eddine, Rima, et al.
Publicado: (2023)

In vivo expression of innate immunity markers in patients with mycobacterium tuberculosis infection
por: Constantoulakis, Pantelis, et al.
Publicado: (2010)

Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site
por: Mendes, Vitor, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v92u78q42lq0bjed167fvoi0et