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Human liver organoids generated with single donor-derived multiple cells rescue mice from acute liver failure
BACKGROUND: Acute liver failure (ALF) is a life-threatening disease with a high mortality rate. However, there are limited treatments or devices available for ALF therapy. Here, we aimed to develop a new strategy for ALF treatment by transplanting functional liver organoids (LOs) generated from sing...
Autores principales: | Nie, Yun-Zhong, Zheng, Yun-Wen, Ogawa, Miyuki, Miyagi, Etsuko, Taniguchi, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763644/ https://www.ncbi.nlm.nih.gov/pubmed/29321049 http://dx.doi.org/10.1186/s13287-017-0749-1 |
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