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Early diagnosis of an isolated primary peripheral T-cell lymphoma masquerading as massive gingival enlargement in a pediatric patient

Lymphomas are malignant neoplasm of the lymphocyte cell lines, classified as either Hodgkin's or non-Hodgkin's lymphoma (NHL). NHL comprises a heterogeneous group of lymphoid neoplasm arising from B-cell, T-cell or natural killer cell with a spectrum of behavior ranging from relatively ind...

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Autores principales: Ghattamaneni, Sravani, Guttikonda, Venkateswara Rao, Yeluri, Sivaranjani, Kolipara, Rajani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763866/
https://www.ncbi.nlm.nih.gov/pubmed/29391718
http://dx.doi.org/10.4103/jomfp.JOMFP_73_15
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author Ghattamaneni, Sravani
Guttikonda, Venkateswara Rao
Yeluri, Sivaranjani
Kolipara, Rajani
author_facet Ghattamaneni, Sravani
Guttikonda, Venkateswara Rao
Yeluri, Sivaranjani
Kolipara, Rajani
author_sort Ghattamaneni, Sravani
collection PubMed
description Lymphomas are malignant neoplasm of the lymphocyte cell lines, classified as either Hodgkin's or non-Hodgkin's lymphoma (NHL). NHL comprises a heterogeneous group of lymphoid neoplasm arising from B-cell, T-cell or natural killer cell with a spectrum of behavior ranging from relatively indolent to highly aggressive and potentially fatal. Peripheral T-cell lymphoma, a variant of NHL, is a disease characterized by the presence of diffuse lymphadenopathy, extranodal involvement, classical B symptoms such as fever (>100.4°F) for 3 consecutive days, weight loss exceeding 10% of body weight in 6 months and drenching night sweats with a tendency for recurrence. Among NHLs, extranodal presentations are relatively common. Extranodal presentation particularly in the oral cavity is very rare and may misinterpret the diagnosis. Lesions of this type should be cautiously dealt especially in pediatric patients and young adolescents. The present case report is about an atypical presentation of disease process in a 15-year-old male patient, which was diagnosed early with the help of a combination of histopathology and immunohistochemistry techniques.
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spelling pubmed-57638662018-02-01 Early diagnosis of an isolated primary peripheral T-cell lymphoma masquerading as massive gingival enlargement in a pediatric patient Ghattamaneni, Sravani Guttikonda, Venkateswara Rao Yeluri, Sivaranjani Kolipara, Rajani J Oral Maxillofac Pathol Case Report Lymphomas are malignant neoplasm of the lymphocyte cell lines, classified as either Hodgkin's or non-Hodgkin's lymphoma (NHL). NHL comprises a heterogeneous group of lymphoid neoplasm arising from B-cell, T-cell or natural killer cell with a spectrum of behavior ranging from relatively indolent to highly aggressive and potentially fatal. Peripheral T-cell lymphoma, a variant of NHL, is a disease characterized by the presence of diffuse lymphadenopathy, extranodal involvement, classical B symptoms such as fever (>100.4°F) for 3 consecutive days, weight loss exceeding 10% of body weight in 6 months and drenching night sweats with a tendency for recurrence. Among NHLs, extranodal presentations are relatively common. Extranodal presentation particularly in the oral cavity is very rare and may misinterpret the diagnosis. Lesions of this type should be cautiously dealt especially in pediatric patients and young adolescents. The present case report is about an atypical presentation of disease process in a 15-year-old male patient, which was diagnosed early with the help of a combination of histopathology and immunohistochemistry techniques. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5763866/ /pubmed/29391718 http://dx.doi.org/10.4103/jomfp.JOMFP_73_15 Text en Copyright: © 2017 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Ghattamaneni, Sravani
Guttikonda, Venkateswara Rao
Yeluri, Sivaranjani
Kolipara, Rajani
Early diagnosis of an isolated primary peripheral T-cell lymphoma masquerading as massive gingival enlargement in a pediatric patient
title Early diagnosis of an isolated primary peripheral T-cell lymphoma masquerading as massive gingival enlargement in a pediatric patient
title_full Early diagnosis of an isolated primary peripheral T-cell lymphoma masquerading as massive gingival enlargement in a pediatric patient
title_fullStr Early diagnosis of an isolated primary peripheral T-cell lymphoma masquerading as massive gingival enlargement in a pediatric patient
title_full_unstemmed Early diagnosis of an isolated primary peripheral T-cell lymphoma masquerading as massive gingival enlargement in a pediatric patient
title_short Early diagnosis of an isolated primary peripheral T-cell lymphoma masquerading as massive gingival enlargement in a pediatric patient
title_sort early diagnosis of an isolated primary peripheral t-cell lymphoma masquerading as massive gingival enlargement in a pediatric patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763866/
https://www.ncbi.nlm.nih.gov/pubmed/29391718
http://dx.doi.org/10.4103/jomfp.JOMFP_73_15
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