Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: A rare case

Oral squamous cell carcinoma with prominent clear-cell differentiation is a rare occurrence with incompletely understood etiology. We report a case of a 55-year-old male working in a steel factory presented with an ulcerated swelling on maxillary alveolar ridge, a rare site. Histopathology showed sh...

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Autores principales: Devi, Anju, Kamboj, Mala, Singh, Virender, Singh, Sunita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763867/
https://www.ncbi.nlm.nih.gov/pubmed/29391719
http://dx.doi.org/10.4103/jomfp.JOMFP_180_16
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author Devi, Anju
Kamboj, Mala
Singh, Virender
Singh, Sunita
author_facet Devi, Anju
Kamboj, Mala
Singh, Virender
Singh, Sunita
author_sort Devi, Anju
collection PubMed
description Oral squamous cell carcinoma with prominent clear-cell differentiation is a rare occurrence with incompletely understood etiology. We report a case of a 55-year-old male working in a steel factory presented with an ulcerated swelling on maxillary alveolar ridge, a rare site. Histopathology showed sheets of squamous cells with clear cell differentiation and features of malignancy. Periodic acid–Schiff and mucicarmine stains showed negative reaction. Immunohistochemical study using antibody for cytokeratin and epithelial membrane antigen revealed diffuse and intense positivity. The neoplastic cells showed complete negative reaction with antibodies for S-100 and vimentin.
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spelling pubmed-57638672018-02-01 Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: A rare case Devi, Anju Kamboj, Mala Singh, Virender Singh, Sunita J Oral Maxillofac Pathol Case Report Oral squamous cell carcinoma with prominent clear-cell differentiation is a rare occurrence with incompletely understood etiology. We report a case of a 55-year-old male working in a steel factory presented with an ulcerated swelling on maxillary alveolar ridge, a rare site. Histopathology showed sheets of squamous cells with clear cell differentiation and features of malignancy. Periodic acid–Schiff and mucicarmine stains showed negative reaction. Immunohistochemical study using antibody for cytokeratin and epithelial membrane antigen revealed diffuse and intense positivity. The neoplastic cells showed complete negative reaction with antibodies for S-100 and vimentin. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5763867/ /pubmed/29391719 http://dx.doi.org/10.4103/jomfp.JOMFP_180_16 Text en Copyright: © 2017 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Devi, Anju
Kamboj, Mala
Singh, Virender
Singh, Sunita
Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: A rare case
title Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: A rare case
title_full Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: A rare case
title_fullStr Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: A rare case
title_full_unstemmed Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: A rare case
title_short Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: A rare case
title_sort clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: a rare case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763867/
https://www.ncbi.nlm.nih.gov/pubmed/29391719
http://dx.doi.org/10.4103/jomfp.JOMFP_180_16
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AT singhsunita clearcellvariantofsquamouscellcarcinomainmaxillaasprimarylesionararecase

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