Molecular Circuits of Resolution in Renal Disease

Inflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting the cytokine milieu from proinflammatory to p...

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Detalles Bibliográficos
Autores principales: Börgeson, Emma, Godson, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763933/
https://www.ncbi.nlm.nih.gov/pubmed/20623097
http://dx.doi.org/10.1100/tsw.2010.120
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author Börgeson, Emma
Godson, Catherine
author_facet Börgeson, Emma
Godson, Catherine
author_sort Börgeson, Emma
collection PubMed
description Inflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting the cytokine milieu from proinflammatory to proresolving and increasing the nonphlogistic phagocytosis of apoptotic cells by macrophages. Here we review the evidence for molecular circuits of resolution in renal disease.
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spelling pubmed-57639332018-06-03 Molecular Circuits of Resolution in Renal Disease Börgeson, Emma Godson, Catherine ScientificWorldJournal Review Article Inflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting the cytokine milieu from proinflammatory to proresolving and increasing the nonphlogistic phagocytosis of apoptotic cells by macrophages. Here we review the evidence for molecular circuits of resolution in renal disease. TheScientificWorldJOURNAL 2010-07-07 /pmc/articles/PMC5763933/ /pubmed/20623097 http://dx.doi.org/10.1100/tsw.2010.120 Text en Copyright © 2010 Emma Börgeson and Catherine Godson. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Börgeson, Emma
Godson, Catherine
Molecular Circuits of Resolution in Renal Disease
title Molecular Circuits of Resolution in Renal Disease
title_full Molecular Circuits of Resolution in Renal Disease
title_fullStr Molecular Circuits of Resolution in Renal Disease
title_full_unstemmed Molecular Circuits of Resolution in Renal Disease
title_short Molecular Circuits of Resolution in Renal Disease
title_sort molecular circuits of resolution in renal disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763933/
https://www.ncbi.nlm.nih.gov/pubmed/20623097
http://dx.doi.org/10.1100/tsw.2010.120
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