Environmental enrichment intervention for Rett syndrome: an individually randomised stepped wedge trial

BACKGROUND: Rett syndrome is caused by a pathogenic mutation in the MECP2 gene with major consequences for motor and cognitive development. One of the effects of impaired MECP2 function is reduced production of Brain Derived Neurotrophic Factor (BDNF), a protein required for normal neuronal developm...

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Detalles Bibliográficos
Autores principales: Downs, Jenny, Rodger, Jenny, Li, Chen, Tan, Xuesong, Hu, Nan, Wong, Kingsley, de Klerk, Nicholas, Leonard, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764021/
https://www.ncbi.nlm.nih.gov/pubmed/29321033
http://dx.doi.org/10.1186/s13023-017-0752-8

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