Notch signaling triggered via the ligand DLL4 impedes M2 macrophage differentiation and promotes their apoptosis

BACKGROUND: Notch signaling controls many cellular processes, including cell fate determination, cell differentiation, proliferation and apoptosis. In mammals, four Notch receptors (Notch 1–4) can interact with five distinct ligands [Jagged1, Jagged2, Delta-like 1 (DLL1), DLL3, and DLL4]. We previou...

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Detalles Bibliográficos
Autores principales: Pagie, Sylvain, Gérard, Nathalie, Charreau, Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764024/
https://www.ncbi.nlm.nih.gov/pubmed/29321062
http://dx.doi.org/10.1186/s12964-017-0214-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764024/
https://www.ncbi.nlm.nih.gov/pubmed/29321062
http://dx.doi.org/10.1186/s12964-017-0214-x

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