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Notch signaling triggered via the ligand DLL4 impedes M2 macrophage differentiation and promotes their apoptosis
BACKGROUND: Notch signaling controls many cellular processes, including cell fate determination, cell differentiation, proliferation and apoptosis. In mammals, four Notch receptors (Notch 1–4) can interact with five distinct ligands [Jagged1, Jagged2, Delta-like 1 (DLL1), DLL3, and DLL4]. We previou...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764024/ https://www.ncbi.nlm.nih.gov/pubmed/29321062 http://dx.doi.org/10.1186/s12964-017-0214-x |