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Specific oxygenation of plasma membrane phospholipids by Pseudomonas aeruginosa lipoxygenase induces structural and functional alterations in mammalian cells
Pseudomonas aeruginosa is a gram-negative pathogen, which causes life-threatening infections in immunocompromized patients. These bacteria express a secreted lipoxygenase (PA-LOX), which oxygenates free arachidonic acid to 15S-hydro(pero)xyeicosatetraenoic acid. It binds phospholipids at its active...
Autores principales: | Aldrovandi, Maceler, Banthiya, Swathi, Meckelmann, Sven, Zhou, You, Heydeck, Dagmar, O'Donnell, Valerie B., Kuhn, Hartmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764228/ https://www.ncbi.nlm.nih.gov/pubmed/29146531 http://dx.doi.org/10.1016/j.bbalip.2017.11.005 |
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