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MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice
In Huntington's disease (HD) patients and in model organisms, messenger RNA transcriptome has been extensively studied; in contrast, comparatively little is known about expression and potential role of microRNAs. Using RNA-sequencing, we have quantified microRNA expression in four brain regions...
Autores principales: | Langfelder, Peter, Gao, Fuying, Wang, Nan, Howland, David, Kwak, Seung, Vogt, Thomas F., Aaronson, Jeffrey S., Rosinski, Jim, Coppola, Giovanni, Horvath, Steve, Yang, X. William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764268/ https://www.ncbi.nlm.nih.gov/pubmed/29324753 http://dx.doi.org/10.1371/journal.pone.0190550 |
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