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SIRT3 activator Honokiol attenuates β-Amyloid by modulating amyloidogenic pathway

Honokiol (poly-phenolic lignan from Magnolia grandiflora) is a Sirtuin-3 (SIRT3) activator which exhibit antioxidant activity and augment mitochondrial functions in several experimental models. Modern evidence suggests the critical role of SIRT3 in the progression of several metabolic and neurodegen...

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Detalles Bibliográficos
Autores principales: Ramesh, Sindhu, Govindarajulu, Manoj, Lynd, Tyler, Briggs, Gwyneth, Adamek, Danielle, Jones, Ellery, Heiner, Jake, Majrashi, Mohammed, Moore, Timothy, Amin, Rajesh, Suppiramaniam, Vishnu, Dhanasekaran, Muralikrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764272/
https://www.ncbi.nlm.nih.gov/pubmed/29324783
http://dx.doi.org/10.1371/journal.pone.0190350