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lin-4 and the NRDE pathway are required to activate a transgenic lin-4 reporter but not the endogenous lin-4 locus in C. elegans

As the founding member of the microRNA (miRNA) gene family, insights into lin-4 regulation and function have laid a conceptual foundation for countless miRNA-related studies that followed. We previously showed that a transcriptional lin-4 reporter in C. elegans was positively regulated by a lin-4-co...

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Detalles Bibliográficos
Autores principales: Jiao, Alan L., Foster, Daniel J., Dixon, Julia, Slack, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764303/
https://www.ncbi.nlm.nih.gov/pubmed/29324872
http://dx.doi.org/10.1371/journal.pone.0190766