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lin-4 and the NRDE pathway are required to activate a transgenic lin-4 reporter but not the endogenous lin-4 locus in C. elegans
As the founding member of the microRNA (miRNA) gene family, insights into lin-4 regulation and function have laid a conceptual foundation for countless miRNA-related studies that followed. We previously showed that a transcriptional lin-4 reporter in C. elegans was positively regulated by a lin-4-co...
Autores principales: | Jiao, Alan L., Foster, Daniel J., Dixon, Julia, Slack, Frank J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764303/ https://www.ncbi.nlm.nih.gov/pubmed/29324872 http://dx.doi.org/10.1371/journal.pone.0190766 |
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