Reversed graph embedding resolves complex single-cell trajectories

Single-cell trajectories can unveil how gene regulation governs cell fate decisions. However, learning the structure of complex trajectories with two or more branches remains a challenging computational problem. We present Monocle 2, which uses reversed graph embedding to describe multiple fate deci...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Xiaojie, Mao, Qi, Tang, Ying, Wang, Li, Chawla, Raghav, Pliner, Hannah A., Trapnell, Cole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764547/
https://www.ncbi.nlm.nih.gov/pubmed/28825705
http://dx.doi.org/10.1038/nmeth.4402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764547/
https://www.ncbi.nlm.nih.gov/pubmed/28825705
http://dx.doi.org/10.1038/nmeth.4402

Ejemplares similares