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Reversed graph embedding resolves complex single-cell trajectories
Single-cell trajectories can unveil how gene regulation governs cell fate decisions. However, learning the structure of complex trajectories with two or more branches remains a challenging computational problem. We present Monocle 2, which uses reversed graph embedding to describe multiple fate deci...
Autores principales: | Qiu, Xiaojie, Mao, Qi, Tang, Ying, Wang, Li, Chawla, Raghav, Pliner, Hannah A., Trapnell, Cole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764547/ https://www.ncbi.nlm.nih.gov/pubmed/28825705 http://dx.doi.org/10.1038/nmeth.4402 |
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