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Assessment of PIM-2 performance among surgical patients with heart disease and correlation of results with RACHS-1

OBJECTIVE: To assess the performance of the Pediatric Index of Mortality (PIM) 2 and the Risk Adjustment for Congenital Heart Surgery (RACHS) in the postoperative period of congenital heart disease patients. METHODS: Retrospective cross-sectional study. Data were collected from patient records to ge...

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Autores principales: Rezende, Raíssa Queiroz, Ricachinevsky, Cláudia Pires, Botta, Aline, Angeli, Viviane Rampon, Nogueira, Aldemir José da Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Medicina Intensiva Brasileira - AMIB 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764557/
https://www.ncbi.nlm.nih.gov/pubmed/29340536
http://dx.doi.org/10.5935/0103-507X.20170069
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author Rezende, Raíssa Queiroz
Ricachinevsky, Cláudia Pires
Botta, Aline
Angeli, Viviane Rampon
Nogueira, Aldemir José da Silva
author_facet Rezende, Raíssa Queiroz
Ricachinevsky, Cláudia Pires
Botta, Aline
Angeli, Viviane Rampon
Nogueira, Aldemir José da Silva
author_sort Rezende, Raíssa Queiroz
collection PubMed
description OBJECTIVE: To assess the performance of the Pediatric Index of Mortality (PIM) 2 and the Risk Adjustment for Congenital Heart Surgery (RACHS) in the postoperative period of congenital heart disease patients. METHODS: Retrospective cross-sectional study. Data were collected from patient records to generate the scores and predictions using recommended techniques, demographic data and outcomes. The Mann-Whitney test, Hosmer-Lemeshow test, standardized mortality rate, area under the receiver operating characteristic (ROC) curve, chi square test, Poisson regression with robust variance and Spearman's test were used for statistical analysis. RESULTS: A total of 263 patients were evaluated, and 72 died (27.4%). These patients presented significantly higher PIM-2 values than survivors (p < 0.001). In the RACHS-1 classification, mortality was progressively higher according to the complexity of the procedure, with a 3.24-fold increase in the comparison between groups 6 and 2. The area under the ROC curve for PIM-2 was 0.81 (95%CI 0.75 - 0.87), while for RACHS-1, it was 0.70 (95%CI 0.63 - 0.77). The RACHS presented better calibration power in the sample analyzed. A significantly positive correlation was found between the results of both scores (r(s) = 0.532; p < 0.001). CONCLUSION: RACHS presented good calibration power, and RACHS-1 and PIM-2 demonstrated good performance with regard to their discriminating capacities between survivors and non-survivors. Moreover, a positive correlation was found between the results of the two risk scores.
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spelling pubmed-57645572018-01-17 Assessment of PIM-2 performance among surgical patients with heart disease and correlation of results with RACHS-1 Rezende, Raíssa Queiroz Ricachinevsky, Cláudia Pires Botta, Aline Angeli, Viviane Rampon Nogueira, Aldemir José da Silva Rev Bras Ter Intensiva Original Articles OBJECTIVE: To assess the performance of the Pediatric Index of Mortality (PIM) 2 and the Risk Adjustment for Congenital Heart Surgery (RACHS) in the postoperative period of congenital heart disease patients. METHODS: Retrospective cross-sectional study. Data were collected from patient records to generate the scores and predictions using recommended techniques, demographic data and outcomes. The Mann-Whitney test, Hosmer-Lemeshow test, standardized mortality rate, area under the receiver operating characteristic (ROC) curve, chi square test, Poisson regression with robust variance and Spearman's test were used for statistical analysis. RESULTS: A total of 263 patients were evaluated, and 72 died (27.4%). These patients presented significantly higher PIM-2 values than survivors (p < 0.001). In the RACHS-1 classification, mortality was progressively higher according to the complexity of the procedure, with a 3.24-fold increase in the comparison between groups 6 and 2. The area under the ROC curve for PIM-2 was 0.81 (95%CI 0.75 - 0.87), while for RACHS-1, it was 0.70 (95%CI 0.63 - 0.77). The RACHS presented better calibration power in the sample analyzed. A significantly positive correlation was found between the results of both scores (r(s) = 0.532; p < 0.001). CONCLUSION: RACHS presented good calibration power, and RACHS-1 and PIM-2 demonstrated good performance with regard to their discriminating capacities between survivors and non-survivors. Moreover, a positive correlation was found between the results of the two risk scores. Associação de Medicina Intensiva Brasileira - AMIB 2017 /pmc/articles/PMC5764557/ /pubmed/29340536 http://dx.doi.org/10.5935/0103-507X.20170069 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Rezende, Raíssa Queiroz
Ricachinevsky, Cláudia Pires
Botta, Aline
Angeli, Viviane Rampon
Nogueira, Aldemir José da Silva
Assessment of PIM-2 performance among surgical patients with heart disease and correlation of results with RACHS-1
title Assessment of PIM-2 performance among surgical patients with heart disease and correlation of results with RACHS-1
title_full Assessment of PIM-2 performance among surgical patients with heart disease and correlation of results with RACHS-1
title_fullStr Assessment of PIM-2 performance among surgical patients with heart disease and correlation of results with RACHS-1
title_full_unstemmed Assessment of PIM-2 performance among surgical patients with heart disease and correlation of results with RACHS-1
title_short Assessment of PIM-2 performance among surgical patients with heart disease and correlation of results with RACHS-1
title_sort assessment of pim-2 performance among surgical patients with heart disease and correlation of results with rachs-1
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764557/
https://www.ncbi.nlm.nih.gov/pubmed/29340536
http://dx.doi.org/10.5935/0103-507X.20170069
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