Posterior tibial artery aneurysm in a child with SMAD3 mutation

Peripheral arterial aneurysms in children are uncommon. We report a 6-year-old boy who developed a right posterior tibial artery aneurysm with symptoms including pain and pulsatile tenderness. His genetic testing revealed a SMAD3 mutation, a condition associated with familial aortic aneurysm, early-...

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Detalles Bibliográficos
Autores principales: Kfoury, Elias, Chen, Aaron Y., Lin, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Complex aortic aneurysm
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764858/
https://www.ncbi.nlm.nih.gov/pubmed/29349393
http://dx.doi.org/10.1016/j.jvscit.2016.07.003
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author Kfoury, Elias
Chen, Aaron Y.
Lin, Peter H.
author_facet Kfoury, Elias
Chen, Aaron Y.
Lin, Peter H.
author_sort Kfoury, Elias
collection PubMed
description Peripheral arterial aneurysms in children are uncommon. We report a 6-year-old boy who developed a right posterior tibial artery aneurysm with symptoms including pain and pulsatile tenderness. His genetic testing revealed a SMAD3 mutation, a condition associated with familial aortic aneurysm, early-onset of osteoarthritis, and peripheral aneurysms. The posterior tibial artery aneurysm was treated with surgical resection and primary anastomosis. The patient remained free of symptoms or aneurysm recurrence in his tibial artery 2 years later. This represents the first reported case of pediatric tibial artery aneurysm linked to a SMAD3 mutation.
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spelling pubmed-57648582018-01-18 Posterior tibial artery aneurysm in a child with SMAD3 mutation Kfoury, Elias Chen, Aaron Y. Lin, Peter H. J Vasc Surg Cases Innov Tech Complex aortic aneurysm Peripheral arterial aneurysms in children are uncommon. We report a 6-year-old boy who developed a right posterior tibial artery aneurysm with symptoms including pain and pulsatile tenderness. His genetic testing revealed a SMAD3 mutation, a condition associated with familial aortic aneurysm, early-onset of osteoarthritis, and peripheral aneurysms. The posterior tibial artery aneurysm was treated with surgical resection and primary anastomosis. The patient remained free of symptoms or aneurysm recurrence in his tibial artery 2 years later. This represents the first reported case of pediatric tibial artery aneurysm linked to a SMAD3 mutation. Elsevier 2017-07-14 /pmc/articles/PMC5764858/ /pubmed/29349393 http://dx.doi.org/10.1016/j.jvscit.2016.07.003 Text en © 2016 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Complex aortic aneurysm
Kfoury, Elias
Chen, Aaron Y.
Lin, Peter H.
Posterior tibial artery aneurysm in a child with SMAD3 mutation
title Posterior tibial artery aneurysm in a child with SMAD3 mutation
title_full Posterior tibial artery aneurysm in a child with SMAD3 mutation
title_fullStr Posterior tibial artery aneurysm in a child with SMAD3 mutation
title_full_unstemmed Posterior tibial artery aneurysm in a child with SMAD3 mutation
title_short Posterior tibial artery aneurysm in a child with SMAD3 mutation
title_sort posterior tibial artery aneurysm in a child with smad3 mutation
topic Complex aortic aneurysm
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764858/
https://www.ncbi.nlm.nih.gov/pubmed/29349393
http://dx.doi.org/10.1016/j.jvscit.2016.07.003
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