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Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration

Contradictory data have been presented regarding the implication of the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome in age-related macular degeneration (AMD), the leading cause of vision loss in the Western world. Recognizing that antibody specificity may explain this discre...

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Detalles Bibliográficos
Autores principales:	Kosmidou, Cassandra, Efstathiou, Nikolaos E., Hoang, Mien V., Notomi, Shoji, Konstantinou, Eleni K., Hirano, Masayuki, Takahashi, Kosuke, Maidana, Daniel E., Tsoka, Pavlina, Young, Lucy, Gragoudas, Evangelos S., Olsen, Timothy W., Morizane, Yuki, Miller, Joan W., Vavvas, Demetrios G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764999/ https://www.ncbi.nlm.nih.gov/pubmed/29323137 http://dx.doi.org/10.1038/s41598-017-17634-1

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