Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters

FGF receptor 2 is involved in the formation of the neuromuscular junction (NMJ), but its in vivo ligand remains to be determined. Laser capture microdissection of the mouse spinal motor neurons (SMNs) revealed that Fgf18 mRNA is highly expressed in SMNs in adults. Expression of Fgf18 mRNA was the hi...

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Detalles Bibliográficos
Autores principales: Ito, Kenyu, Ohkawara, Bisei, Yagi, Hideki, Nakashima, Hiroaki, Tsushima, Mikito, Ota, Kyotaro, Konishi, Hiroyuki, Masuda, Akio, Imagama, Shiro, Kiyama, Hiroshi, Ishiguro, Naoki, Ohno, Kinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765005/
https://www.ncbi.nlm.nih.gov/pubmed/29323161
http://dx.doi.org/10.1038/s41598-017-18753-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765005/
https://www.ncbi.nlm.nih.gov/pubmed/29323161
http://dx.doi.org/10.1038/s41598-017-18753-5

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