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A Tet-Off gene expression system for validation of antifungal drug targets in a murine invasive pulmonary aspergillosis model
Aspergillus fumigatus is one of the major causes of invasive pulmonary aspergillosis in immunocompromised patients. Novel antifungal therapy is in urgent need due to emerging resistance and adverse toxicity of current antifungal drugs. Gene products that are essential for Aspergillus viability durin...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765126/ https://www.ncbi.nlm.nih.gov/pubmed/29323188 http://dx.doi.org/10.1038/s41598-017-18868-9 |