Mapping the operational landscape of microRNAs in synthetic gene circuits

MicroRNAs are a class of short, noncoding RNAs that are ubiquitous modulators of gene expression, with roles in development, homeostasis, and disease. Engineered microRNAs are now frequently used as regulatory modules in synthetic biology. Moreover, synthetic gene circuits equipped with engineered m...

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Detalles Bibliográficos
Autores principales: Quarton, Tyler, Ehrhardt, Kristina, Lee, James, Kannan, Srijaa, Li, Yi, Ma, Lan, Bleris, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765153/
https://www.ncbi.nlm.nih.gov/pubmed/29354284
http://dx.doi.org/10.1038/s41540-017-0043-y

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