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Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal
Accumulation of somatic mutations in mitochondrial DNA (mtDNA) has been proposed to be responsible for human aging and age-associated mitochondrial respiration defects. However, our previous findings suggested an alternative hypothesis of human aging—that epigenetic changes but not mutations regulat...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765156/ https://www.ncbi.nlm.nih.gov/pubmed/29323231 http://dx.doi.org/10.1038/s41598-017-18828-3 |