Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival

Cancer develops by accumulation of somatic driver mutations, which impact cellular function. Mutations in non-coding regulatory regions can now be studied genome-wide and further characterized by correlation with gene expression and clinical outcome to identify driver candidates. Using a new two-sta...

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Detalles Bibliográficos
Autores principales: Hornshøj, Henrik, Nielsen, Morten Muhlig, Sinnott-Armstrong, Nicholas A., Świtnicki, Michał P., Juul, Malene, Madsen, Tobias, Sallari, Richard, Kellis, Manolis, Ørntoft, Torben, Hobolth, Asger, Pedersen, Jakob Skou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765157/
https://www.ncbi.nlm.nih.gov/pubmed/29354286
http://dx.doi.org/10.1038/s41525-017-0040-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765157/
https://www.ncbi.nlm.nih.gov/pubmed/29354286
http://dx.doi.org/10.1038/s41525-017-0040-5

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