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Increased frequencies of circulating CXCL10-, CXCL8- and CCL4-producing monocytes and Siglec-3-expressing myeloid dendritic cells in systemic sclerosis patients
OBJECTIVE: To investigate the ex vivo pro-inflammatory properties of classical and non-classical monocytes as well as myeloid dendritic cells (mDCs) in systemic sclerosis (SSc) patients. METHODS: Spontaneous production of CXCL10, CCL4, CXCL8 and IL-6 was intracellularly evaluated in classical, non-c...
Autores principales: | Carvalheiro, Tiago, Horta, Sara, van Roon, Joel A. G., Santiago, Mariana, Salvador, Maria J., Trindade, Hélder, Radstake, Timothy R. D. J., da Silva, José A. P., Paiva, Artur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765192/ https://www.ncbi.nlm.nih.gov/pubmed/29127442 http://dx.doi.org/10.1007/s00011-017-1106-7 |
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