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Targeting de novo lipogenesis as a novel approach in anti-cancer therapy
BACKGROUND: Although altered membrane physiology has been discussed within the context of cancer, targeting membrane characteristics by drugs being an attractive therapeutic strategy has received little attention so far. METHODS: Various acetyl-CoA carboxylase 1 (ACC1), and fatty acid synthase (FASN...
Autores principales: | Stoiber, Katharina, Nagło, Olga, Pernpeintner, Carla, Zhang, Siwei, Koeberle, Andreas, Ulrich, Melanie, Werz, Oliver, Müller, Rolf, Zahler, Stefan, Lohmüller, Theobald, Feldmann, Jochen, Braig, Simone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765225/ https://www.ncbi.nlm.nih.gov/pubmed/29112683 http://dx.doi.org/10.1038/bjc.2017.374 |
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