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Mechanisms of resistance to immune checkpoint inhibitors

Immune checkpoint inhibitors (ICI) targeting CTLA-4 and the PD-1/PD-L1 axis have shown unprecedented clinical activity in several types of cancer and are rapidly transforming the practice of medical oncology. Whereas cytotoxic chemotherapy and small molecule inhibitors (‘targeted therapies’) largely...

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Detalles Bibliográficos
Autores principales:	Jenkins, Russell W, Barbie, David A, Flaherty, Keith T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765236/ https://www.ncbi.nlm.nih.gov/pubmed/29319049 http://dx.doi.org/10.1038/bjc.2017.434

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