Optimization of capillary zone electrophoresis for charge heterogeneity testing of biopharmaceuticals using enhanced method development principles

CZE is a well‐established technique for charge heterogeneity testing of biopharmaceuticals. It is based on the differences between the ratios of net charge and hydrodynamic radius. In an extensive intercompany study, it was recently shown that CZE is very robust and can be easily implemented in labs...

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Detalles Bibliográficos
Autores principales: Moritz, Bernd, Locatelli, Valentina, Niess, Michele, Bathke, Andrea, Kiessig, Steffen, Entler, Barbara, Finkler, Christof, Wegele, Harald, Stracke, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Part III. Methodologies and Applications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765393/
https://www.ncbi.nlm.nih.gov/pubmed/28887890
http://dx.doi.org/10.1002/elps.201700145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765393/
https://www.ncbi.nlm.nih.gov/pubmed/28887890
http://dx.doi.org/10.1002/elps.201700145

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