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NEAT1 Scaffolds RNA Binding Proteins and the Microprocessor to Globally Enhance Pri-miRNA Processing
MicroRNA biogenesis is known to be modulated by a variety of RNA binding proteins (RBPs), but in most cases, individual RBPs appear to influence the processing of a small subset of target miRNAs. We herein report that the RNA binding NONO/PSF heterodimer binds a large number of expressed pri-miRNAs...
Autores principales: | Jiang, Li, Shao, Changwei, Wu, Qi-Jia, Chen, Geng, Zhou, Jie, Yang, Bo, Li, Hairi, Gou, Lan-Tao, Zhang, Yi, Wang, Yangming, Yeo, Gene W., Zhou, Yu, Fu, Xiang-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766049/ https://www.ncbi.nlm.nih.gov/pubmed/28846091 http://dx.doi.org/10.1038/nsmb.3455 |
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