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A novel method to test associations between a weighted combination of phenotypes and genetic variants
Many complex diseases like diabetes, hypertension, metabolic syndrome, et cetera, are measured by multiple correlated phenotypes. However, most genome-wide association studies (GWAS) focus on one phenotype of interest or study multiple phenotypes separately for identifying genetic variants associate...
Autores principales: | Zhu, Huanhuan, Zhang, Shuanglin, Sha, Qiuying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766098/ https://www.ncbi.nlm.nih.gov/pubmed/29329304 http://dx.doi.org/10.1371/journal.pone.0190788 |
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