Modeling the effect of boost timing in murine irradiated sporozoite prime-boost vaccines

Vaccination with radiation-attenuated sporozoites has been shown to induce CD8+ T cell-mediated protection against pre-erythrocytic stages of malaria. Empirical evidence suggests that successive inoculations often improve the efficacy of this type of vaccines. An initial dose (prime) triggers a spec...

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Detalles Bibliográficos
Autores principales: Fernandez-Arias, Cristina, Arias, Clemente F., Zhang, Min, Herrero, Miguel A., Acosta, Francisco J., Tsuji, Moriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766151/
https://www.ncbi.nlm.nih.gov/pubmed/29329308
http://dx.doi.org/10.1371/journal.pone.0190940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766151/
https://www.ncbi.nlm.nih.gov/pubmed/29329308
http://dx.doi.org/10.1371/journal.pone.0190940

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