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Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle

DNA translesion synthesis (TLS) is a crucial damage tolerance pathway that oversees the completion of DNA replication in the presence of DNA damage. TLS polymerases are capable of bypassing a distorted template but they are generally considered inaccurate and they need to be tightly regulated. We ha...

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Detalles Bibliográficos
Autores principales:	Bertoletti, Federica, Cea, Valentina, Liang, Chih-Chao, Lanati, Taiba, Maffia, Antonio, Avarello, Mario D.M., Cipolla, Lina, Lehmann, Alan R., Cohn, Martin A., Sabbioneda, Simone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766190/ https://www.ncbi.nlm.nih.gov/pubmed/28934491 http://dx.doi.org/10.1093/nar/gkx619

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