Cohesin acetyltransferase Esco2 regulates SAC and kinetochore functions via maintaining H4K16 acetylation during mouse oocyte meiosis

Sister chromatid cohesion, mediated by cohesin complex and established by the acetyltransferases Esco1 and Esco2, is essential for faithful chromosome segregation. Mutations in Esco2 cause Roberts syndrome, a developmental disease characterized by severe prenatal retardation as well as limb and faci...

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Detalles Bibliográficos
Autores principales: Lu, Yajuan, Dai, Xiaoxin, Zhang, Mianqun, Miao, Yilong, Zhou, Changyin, Cui, Zhaokang, Xiong, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766191/
https://www.ncbi.nlm.nih.gov/pubmed/28934466
http://dx.doi.org/10.1093/nar/gkx563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766191/
https://www.ncbi.nlm.nih.gov/pubmed/28934466
http://dx.doi.org/10.1093/nar/gkx563

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