Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency

In eukaryotic cells, the gene expression status is strictly controlled by epigenetic modifications on chromatin. The repressive status of chromatin largely contributes to HIV latency. Studies have shown that modification of histone H3K27 acts as a key molecular switch for activation or suppression o...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng, Nikolai, Bryan C., Gates, Leah A., Jung, Sung Yun, Siwak, Edward B., He, Bin, Rice, Andrew P., O’Malley, Bert W., Feng, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766202/
https://www.ncbi.nlm.nih.gov/pubmed/28637181
http://dx.doi.org/10.1093/nar/gkx550

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