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XIAP upregulates expression of HIF target genes by targeting HIF1α for Lys(63)-linked polyubiquitination
The cellular response to hypoxia is characterised by a switch in the transcriptional program, mediated predominantly by the hypoxia inducible factor family of transcription factors (HIF). Regulation of HIF1 is primarily controlled by post-translational modification of the HIF1α subunit, which can al...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766203/ https://www.ncbi.nlm.nih.gov/pubmed/28666324 http://dx.doi.org/10.1093/nar/gkx549 |