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Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

Copper(II) ternary complex, [Cu(phen)(C-dmg)(H(2)O)]NO(3) was evaluated against a panel of cell lines, tested for in vivo efficacy in nasopharyngeal carcinoma xenograft models as well as for toxicity in NOD scid gamma mice. The Cu(II) complex displayed broad spectrum cytotoxicity against multiple ca...

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Detalles Bibliográficos
Autores principales:	Ahmad, Munirah, Suhaimi, Shazlan-Noor, Chu, Tai-Lin, Abdul Aziz, Norazlin, Mohd Kornain, Noor-Kaslina, Samiulla, D. S., Lo, Kwok-Wai, Ng, Chew-Hee, Khoo, Alan Soo-Beng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766233/ https://www.ncbi.nlm.nih.gov/pubmed/29329342 http://dx.doi.org/10.1371/journal.pone.0191295

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