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Targeting melanoma stem cells with the Vitamin E derivative δ-tocotrienol
The prognosis of metastatic melanoma is very poor, due to the development of drug resistance. Cancer stem cells (CSCs) may play a crucial role in this mechanism, contributing to disease relapse. We first characterized CSCs in melanoma cell lines. We observed that A375 (but not BLM) cells are able to...
Autores principales: | Marzagalli, Monica, Moretti, Roberta Manuela, Messi, Elio, Marelli, Marina Montagnani, Fontana, Fabrizio, Anastasia, Alessia, Bani, Maria Rosa, Beretta, Giangiacomo, Limonta, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766483/ https://www.ncbi.nlm.nih.gov/pubmed/29330434 http://dx.doi.org/10.1038/s41598-017-19057-4 |
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