Development of a PET radioligand for potassium channels to image CNS demyelination

Central nervous system (CNS) demyelination represents the pathological hallmark of multiple sclerosis (MS) and contributes to other neurological conditions. Quantitative and specific imaging of demyelination would thus provide critical clinical insight. Here, we investigated the possibility of targe...

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Detalles Bibliográficos
Autores principales: Brugarolas, Pedro, Sánchez-Rodríguez, Jorge E., Tsai, Hsiu-Ming, Basuli, Falguni, Cheng, Shih-Hsun, Zhang, Xiang, Caprariello, Andrew V., Lacroix, Jerome J., Freifelder, Richard, Murali, Dhanabalan, DeJesus, Onofre, Miller, Robert H., Swenson, Rolf E., Chen, Chin-Tu, Herscovitch, Peter, Reich, Daniel S., Bezanilla, Francisco, Popko, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766510/
https://www.ncbi.nlm.nih.gov/pubmed/29330383
http://dx.doi.org/10.1038/s41598-017-18747-3

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