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Target engagement imaging of PARP inhibitors in small-cell lung cancer

Insufficient chemotherapy response and rapid disease progression remain concerns for small-cell lung cancer (SCLC). Oncologists rely on serial CT scanning to guide treatment decisions, but this cannot assess in vivo target engagement of therapeutic agents. Biomarker assessments in biopsy material do...

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Detalles Bibliográficos
Autores principales:	Carney, Brandon, Kossatz, Susanne, Lok, Benjamin H., Schneeberger, Valentina, Gangangari, Kishore K., Pillarsetty, Naga Vara Kishore, Weber, Wolfgang A., Rudin, Charles M., Poirier, John T., Reiner, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766608/ https://www.ncbi.nlm.nih.gov/pubmed/29330466 http://dx.doi.org/10.1038/s41467-017-02096-w

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