Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis

Epstein–Barr virus (EBV) is a ubiquitous virus that infects nearly all people worldwide without serious sequela. However, for patients who have genetic diseases which predispose them to the development of hemophagocytic lymphohistiocytosis (HLH), EBV infection is a life-threatening problem. As a par...

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Detalles Bibliográficos
Autor principal: Marsh, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766650/
https://www.ncbi.nlm.nih.gov/pubmed/29358936
http://dx.doi.org/10.3389/fimmu.2017.01902
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author Marsh, Rebecca A.
author_facet Marsh, Rebecca A.
author_sort Marsh, Rebecca A.
collection PubMed
description Epstein–Barr virus (EBV) is a ubiquitous virus that infects nearly all people worldwide without serious sequela. However, for patients who have genetic diseases which predispose them to the development of hemophagocytic lymphohistiocytosis (HLH), EBV infection is a life-threatening problem. As a part of a themed collection of articles on EBV infection and human primary immune deficiencies, we will review key concepts related to the understanding and treatment of HLH.
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spelling pubmed-57666502018-01-22 Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis Marsh, Rebecca A. Front Immunol Immunology Epstein–Barr virus (EBV) is a ubiquitous virus that infects nearly all people worldwide without serious sequela. However, for patients who have genetic diseases which predispose them to the development of hemophagocytic lymphohistiocytosis (HLH), EBV infection is a life-threatening problem. As a part of a themed collection of articles on EBV infection and human primary immune deficiencies, we will review key concepts related to the understanding and treatment of HLH. Frontiers Media S.A. 2018-01-08 /pmc/articles/PMC5766650/ /pubmed/29358936 http://dx.doi.org/10.3389/fimmu.2017.01902 Text en Copyright © 2018 Marsh. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Marsh, Rebecca A.
Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_full Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_fullStr Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_full_unstemmed Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_short Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_sort epstein–barr virus and hemophagocytic lymphohistiocytosis
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766650/
https://www.ncbi.nlm.nih.gov/pubmed/29358936
http://dx.doi.org/10.3389/fimmu.2017.01902
work_keys_str_mv AT marshrebeccaa epsteinbarrvirusandhemophagocyticlymphohistiocytosis

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