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An optimized targeted Next-Generation Sequencing approach for sensitive detection of single nucleotide variants

Monitoring of minimal residual disease (MRD) has become an important clinical aspect for early relapse detection during follow-up care after cancer treatment. Still, the sensitive detection of single base pair point mutations via Next-Generation Sequencing (NGS) is hampered mainly due to high substi...

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Detalles Bibliográficos
Autores principales:	Stasik, S., Schuster, C., Ortlepp, C., Platzbecker, U., Bornhäuser, M., Schetelig, J., Ehninger, G., Folprecht, G., Thiede, C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766748/ https://www.ncbi.nlm.nih.gov/pubmed/29349042 http://dx.doi.org/10.1016/j.bdq.2017.12.001

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